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1

Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties

Nordin, Joel Z., Lee, Yi, Vader, Pieter, Mäger, Imre, Johansson, Henrik J., Heusermann, Wolf, Wiklander, Oscar P.B., Hällbrink, Mattias, Seow, Yiqi, Bultema, Jarred J., Gilthorpe, Jonathan, Davies, Ti

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 889 KB

english, 2015

2

Metallic Zinc Reduction of Disulfide Bonds between Cysteine Residues in Peptides and Proteins

Mikael Erlandsson, Mattias Hällbrink

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2005

Language:

english

File:

PDF, 178 KB

english, 2005

3

Prediction of Cell-Penetrating Peptides

Mattias Hällbrink, Kalle Kilk, Anna Elmquist, Pontus Lundberg, Maria Lindgren, Yang Jiang, Margus Pooga, Ursel Soomets, Ülo Langel

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2005

Language:

english

File:

PDF, 538 KB

english, 2005

4

Cell-Penetrating Mimics of Agonist-Activated G-Protein Coupled Receptors

Pernilla Östlund, Kalle Kilk, Maria Lindgren, Mattias Hällbrink, Yang Jiang, Metka Budihna, Katarina Cerne, Aljosa Bavec, Claes-Göran Östenson, Matjaz Zorko, Ülo Langel

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2005

Language:

english

File:

PDF, 360 KB

english, 2005

5

Galanin-Based Peptides, Galparan and Transportan, with Receptor-Dependent and Independent Activities

MARGUS POOGA, MARIA LINDGREN, MATTIAS HÄLLBRINK, EBBA BRÅKENHIELM, ÜLO LANGEL

Journal:

Annals of the New York Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 52 KB

english, 1998

6

Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo

Pooga, Margus, Soomets, Ursel, Hällbrink, Mattias, Valkna, Andres, Saar, Külliki, Rezaei, Khadijeh, Kahl, Ulrika, Hao, Jing-Xia, Xu, Xiao-Jun, Wiesenfeld-Hallin, Zsuzsanna

Journal:

Nature Biotechnology

Year:

1998

File:

PDF, 606 KB

1998

7

Overcoming methotrexate resistance in breast cancer tumour cells by the use of a new cell-penetrating peptide

Maria Lindgren, Katri Rosenthal-Aizman, Külliki Saar, Emelía Eiríksdóttir, Yang Jiang, Meeri Sassian, Pernilla Östlund, Mattias Hällbrink, Ülo Langel

Journal:

Biochemical Pharmacology

Year:

2006

Language:

english

File:

PDF, 372 KB

english, 2006

8

Preferential Uptake of L- versus D-Amino Acid Cell-Penetrating Peptides in a Cell Type-Dependent Manner

Wouter P.R. Verdurmen, Petra H. Bovee-Geurts, Parvesh Wadhwani, Anne S. Ulrich, Mattias Hällbrink, Toin H. van Kuppevelt, Roland Brock

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1.42 MB

english, 2011

9

Amphipathic CPPs upregulate Ca in cells’ cytosol and induce lysosomal exocytosis

A. Lorents, N. Oskolkov, T. Tõnissoo, Ü. Langel, M. Hällbrink, M. Pooga

Journal:

Drug Discovery Today

Year:

2010

Language:

english

File:

PDF, 64 KB

english, 2010

10

A new rapid cell-penetrating peptide based strategy to produce bacterial ghosts for plasmid delivery

Caroline Palm-Apergi, Mattias Hällbrink

Journal:

Journal of Controlled Release

Year:

2008

Language:

english

File:

PDF, 1.15 MB

english, 2008

11

Biochemical mechanisms of calcium mobilisation induced by mastoparan and chimeric hormonewmastoparan constructs

Clare L. Longland, Mokdad Mezna, Ülo Langel, Mattias Hällbrink, Ursel Soomets, Mark Wheatley, Francesco Michelangeli, John Howl

Journal:

Year:

1998

Language:

english

File:

PDF, 799 KB

english, 1998

12

Different domains in the third intracellular loop of the GLP-1 receptor are responsible for Gαs and Gαi/Gαo activation

Mattias Hällbrink, Tomas Holmqvist, Magnus Olsson, Claes-Göran Östenson, Suad Efendic, Ülo Langel

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

2001

Language:

english

File:

PDF, 242 KB

english, 2001

13

Overexpression of Protein-Tyrosine Phosphatase PTPσ Is Linked to Impaired Glucose-Induced Insulin Secretion in Hereditary Diabetic Goto-Kakizaki Rats

Claes-Göran Östenson, Ann-Christine Sandberg-Nordqvist, Jie Chen, Mattias Hällbrink, Daniela Rotin, Ülo Langel, Suad Efendic

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 778 KB

english, 2002

14

Uptake of cell-penetrating peptides is dependent on peptide-to-cell ratio rather than on peptide concentration

Mattias Hällbrink, Johannes Oehlke, Gisela Papsdorf, Michael Bienert

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2004

Language:

english

File:

PDF, 270 KB

english, 2004

15

Peptide degradation is a critical determinant for cell-penetrating peptide uptake

Caroline Palm, Mala Jayamanne, Marcus Kjellander, Mattias Hällbrink

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2007

Language:

english

File:

PDF, 415 KB

english, 2007

16

Uptake of cell-penetrating peptides in yeasts

Tina Holm, Semharai Netzereab, Mats Hansen, Ülo Langel, Mattias Hällbrink

Journal:

Year:

2005

Language:

english

File:

PDF, 298 KB

english, 2005

17

Quantitatively determined uptake of cell-penetrating peptides in non-mammalian cells with an evaluation of degradation and antimicrobial effects

Caroline Palm, Semharai Netzereab, Mattias Hällbrink

Journal:

Year:

2006

Language:

english

File:

PDF, 162 KB

english, 2006

18

Deletion analogues of transportan

Ursel Soomets, Maria Lindgren, Xavier Gallet, Mattias Hällbrink, Anna Elmquist, Lajos Balaspiri, Matjaz Zorko, Margus Pooga, Robert Brasseur, Ülo Langel

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2000

Language:

english

File:

PDF, 517 KB

english, 2000

19

Cargo delivery kinetics of cell-penetrating peptides

Mattias Hällbrink, Anders Florén, Anna Elmquist, Margus Pooga, Tamas Bartfai, Ülo Langel

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2001

Language:

english

File:

PDF, 430 KB

english, 2001

20

Cell membrane translocation of the N-terminal (1–28) part of the prion protein

P Lundberg, M Magzoub, M Lindberg, M Hällbrink, J Jarvet, L.E.G Eriksson, Ü Langel, A Gräslund

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 205 KB

english, 2002

21

Cell-penetrating peptides

Maria Lindgren, Mattias Hällbrink, Alain Prochiantz, Ülo Langel

Journal:

Trends in Pharmacological Sciences

Year:

2000

Language:

english

File:

PDF, 87 KB

english, 2000

22

Different role of intracellular loops of glucagon-like peptide-1 receptor in G-protein coupling

Aljoša Bavec, Mattias Hällbrink, Ülo Langel, Matjaž Zorko

Journal:

Regulatory Peptides

Year:

2003

Language:

english

File:

PDF, 235 KB

english, 2003

23

Effects of vasopressin–mastoparan chimeric peptides on insulin release and G-protein activity

Mattias Hällbrink, Külliki Saar, Claes-Göran Östenson, Ursel Soomets, Suad Efendic, John Howl, Mark Wheatley, Matjaz Zorko, Ülo Langel

Journal:

Regulatory Peptides

Year:

1999

Language:

english

File:

PDF, 116 KB

english, 1999

24

Tumour Targeting with Rationally Modified Cell-Penetrating Peptides

Maarja Mäe, Outi Rautsi, Juulia Enbäck, Mattias Hällbrink, Katri Rosenthal Aizman, Maria Lindgren, Pirjo Laakkonen, Ülo Langel

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2012

Language:

english

File:

PDF, 622 KB

english, 2012

25

Molecular Parameters of siRNA–Cell Penetrating Peptide Nanocomplexes for Efficient Cellular Delivery

van Asbeck, Alexander H., Beyerle, Andrea, McNeill, Hesta, Bovee-Geurts, Petra H.M., Lindberg, Staffan, Verdurmen, Wouter P. R., Hällbrink, Mattias, Langel, Ülo, Heidenreich, Olaf, Brock, Roland

Journal:

Year:

2013

Language:

english

File:

PDF, 1.62 MB

english, 2013

26

Translocation Properties of Novel Cell Penetrating Transportan and Penetratin Analogues

Lindgren, Maria, Gallet, Xavier, Soomets, Ursel, Hällbrink, Mattias, Bråkenhielm, Ebba, Pooga, Margus, Brasseur, Robert, Langel, Ülo

Journal:

Bioconjugate Chemistry

Year:

2000

Language:

english

File:

PDF, 197 KB

english, 2000

27

Peptide-Based Delivery of Oligonucleotides Across Blood–Brain Barrier Model

Srimanee, Artita, Regberg, Jakob, Hallbrink, Mattias, Kurrikoff, Kaido, Veiman, Kadi-Liis, Vajragupta, Opa, Langel, Ülo

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2014

Language:

english

File:

PDF, 421 KB

english, 2014

28

Peptide Nanoparticle Delivery of Charge-Neutral Splice-Switching Morpholino Oligonucleotides

Järver, Peter, Zaghloul, Eman M., Arzumanov, Andrey A., Saleh, Amer F., McClorey, Graham, Hammond, Suzan M., Hällbrink, Mattias, Langel, Ülo, Smith, C.I. Edvard, Wood, Matthew J.A., Gait, Michael J.,

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2015

Language:

english

File:

PDF, 602 KB

english, 2015

29

Passage of cell-penetrating peptides across a human epithelial cell layer in vitro

LINDGREN, Maria E., HÄLLBRINK, Mattias M., ELMQUIST, Anna M., LANGEL, Ülo

Journal:

Biochemical Journal

Year:

2004

Language:

english

File:

PDF, 206 KB

english, 2004

30

Cell-penetrating Peptides Split into Two Groups Based on Modulation of Intracellular Calcium Concentration

Lorents, A., Kodavali, P. K., Oskolkov, N., Langel, U., Hallbrink, M., Pooga, M.

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 3.35 MB

english, 2012

31

The membrane repair response masks membrane disturbances caused by cell-penetrating peptide uptake

Palm-Apergi, C., Lorents, A., Padari, K., Pooga, M., Hallbrink, M.

Journal:

The FASEB Journal

Year:

2009

Language:

english

File:

PDF, 486 KB

english, 2009

32

Role of scavenger receptors in peptide-based delivery of plasmid DNA across a blood–brain barrier model

Srimanee, Artita, Regberg, Jakob, Hällbrink, Mattias, Vajragupta, Opa, Langel, Ülo

Journal:

International Journal of Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 910 KB

english, 2016

33

pH-responsive PepFect cell-penetrating peptides

Regberg, Jakob, Vasconcelos, Luis, Madani, Fatemeh, Langel, Ülo, Hällbrink, Mattias

Journal:

International Journal of Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 1.30 MB

english, 2016

34

Refinement of a Quantitative Structure–Activity Relationship Model for Prediction of Cell-Penetrating Peptide Based Transfection Systems

Dowaidar, Moataz, Regberg, Jakob, Dobchev, Dimitar A., Lehto, Tõnis, Hällbrink, Mattias, Karelson, Mati, Langel, Ülo

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2017

Language:

english

File:

PDF, 1.32 MB

english, 2017

35

Calcium-mobilizing actions of chimeric hormone-mastoparan peptides

MEZNA, MOKDAD, LANGEL, ÜLO, HÄLLBRINK, MATTIAS, WHEATLEY, MARK, MICHELANGELI, FRANCESCO, HOWL, JOHN

Journal:

Biochemical Society Transactions

Year:

1997

Language:

english

File:

PDF, 111 KB

english, 1997

36

Deletion analogues of transportan

Soomets, U., Lindgren, M., Gallet, X., Hällbrink, M., Elmquist, A., Balaspiri, L., Zorko, M., Pooga, M., Brasseur, R., Langel, Ü.

Journal:

Biochemical Society Transactions

Year:

2000

Language:

english

File:

PDF, 137 KB

english, 2000

37

Cellular translocation of proteins by transportan

Pooga, M., Kut, C., Kihlmark, M., Raid, R., Hällbrink, M., Hallberg, E., Langel, Ü.

Journal:

Biochemical Society Transactions

Year:

2000

Language:

english

File:

PDF, 142 KB

english, 2000

38

Saturated Fatty Acid Analogues of Cell-Penetrating Peptide PepFect14: Role of Fatty Acid Modification in Complexation and Delivery of Splice-Correcting Oligonucleotides

Lehto, Tõnis, Vasconcelos, Luis, Margus, Helerin, Figueroa, Ricardo, Pooga, Margus, Hällbrink, Mattias, Langel, Ülo

Journal:

Bioconjugate Chemistry

Year:

2017

Language:

english

File:

PDF, 4.20 MB

english, 2017

39

CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression

Zaghloul, Eman M., Gissberg, Olof, Moreno, Pedro M.D., Siggens, Lee, Hällbrink, Mattias, Jørgensen, Anna S., Ekwall, Karl, Zain, Rula, Wengel, Jesper, Lundin, Karin E., Smith, C.I. Edvard

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 12.28 MB

english, 2017

40

Magnetic Nanoparticle Assisted Self-assembly of Cell Penetrating Peptides-Oligonucleotides Complexes for Gene Delivery

Dowaidar, Moataz, Abdelhamid, Hani Nasser, Hällbrink, Mattias, Freimann, Krista, Kurrikoff, Kaido, Zou, Xiaodong, Langel, Ülo

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 3.20 MB

english, 2017

41

Simultaneous membrane interaction of amphipathic peptide monomers, self-aggregates and cargo complexes detected by fluorescence correlation spectroscopy

Vasconcelos, Luís, Lehto, Tõnis, Madani, Fatemeh, Radoi, Vlad, Hällbrink, Mattias, Vukojević, Vladana, Langel, Ülo

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2017

Language:

english

File:

PDF, 2.35 MB

english, 2017

42

Role of autophagy in cell-penetrating peptide transfection model

Dowaidar, Moataz, Gestin, Maxime, Cerrato, Carmine Pasquale, Jafferali, Mohammed Hakim, Margus, Helerin, Kivistik, Paula Ann, Ezzat, Kariem, Hallberg, Einar, Pooga, Margus, Hällbrink, Mattias, Langel,

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 2.68 MB

english, 2017

43

Cell-penetrating peptides for siRNA delivery to glioblastomas

Srimanee, Artita, Arvanitidou, Maria, Kim, Kumjee, Hällbrink, Mattias, Langel, Ülo

Journal:

Year:

2018

Language:

english

File:

PDF, 964 KB

english, 2018

44

Cell penetration by transportan

Pooga, Margus, Hällbrink, Mattias, Zorko, Matjal, Langel, Uuml, lo

Journal:

The FASEB Journal

Year:

1998

Language:

english

File:

PDF, 527 KB

english, 1998

45

Chitosan enhances gene delivery of oligonucleotide complexes with magnetic nanoparticles–cell-penetrating peptide

Dowaidar, Moataz, Nasser Abdelhamid, Hani, Hällbrink, Mattias, Langel, Ülo, Zou, Xiaodong

Journal:

Journal of Biomaterials Applications

Year:

2018

Language:

english

File:

PDF, 984 KB

english, 2018

46

Peptide-mediated delivery of therapeutic mRNA in ovarian cancer

van den Brand, Dirk, Gorris, Mark A.J., van Asbeck, Alexander H., Palmen, Emma, Ebisch, Inge, Dolstra, Harry, Hällbrink, Mattias, G. Massuger, Leon F.A., Brock, Roland

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2019

Language:

english

File:

PDF, 8.54 MB

english, 2019

47

Peptide-mediated delivery of therapeutic mRNA in ovarian cancer

van den Brand, Dirk, Gorris, Mark A.J., van Asbeck, Alexander H., Palmen, Emma, Ebisch, Inge, Dolstra, Harry, Hällbrink, Mattias, G. Massuger, Leon F.A., Brock, Roland

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2019

File:

PDF, 8.54 MB

2019

48

The nuclear concentration required for antisense oligonucleotide activity in myotonic dystrophy cells

van der Bent, M. Leontien, Paulino da Silva Filho, Omar, Willemse, Marieke, Hällbrink, Mattias, Wansink, Derick G., Brock, Roland

Journal:

The FASEB Journal

Year:

2019

Language:

english

File:

PDF, 1.81 MB

english, 2019

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